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妊娠性蛋白是妊娠期母血中出现的特异蛋白,除已知的绒毛膜促性腺激素(HCG)、胎盘催乳素(HPL)等外,近又发现新的妊娠性蛋白SP_1(妊娠性β_1糖蛋白,pregnancy-specificβ_1-glycoprotein)、SP_3(α_2AP-糖蛋白,α_2AP-glycorotein)。 SP_1,由胎盘合体滋养层合成,于受精后7～20天即可在孕妇血中测得,其量逐渐增加,至妊娠39周达高峰,产后24小时数量减半,到第七天呈微量,产后1个月消失。 SP_3,目前合成部位尚不清楚,Sedlacek认为可能来源于胎盘绒毛基质,由于使用口服避孕药的妇女血中浓度也高,是否在母体其他脏器合成,尚
Gestational protein is a specific protein that appears in maternal blood during pregnancy. In addition to the known HCG and HPL, a new pregnancy protein SP_1 Pregnancy-specific β_1-glycoprotein, SP_3 (α_2AP-glycoprotein, α_2AP-glycorotein). SP_1, synthesized by the placenta syncytiotrophoblast 7 ~ 20 days after fertilization can be measured in the blood of pregnant women, the amount gradually increased to the peak of 39 weeks of pregnancy, the number of 24 hours after delivery in half reduced to the seventh day was trace , Disappeared 1 month after delivery. SP_3, the current synthetic site is not clear, Sedlacek that may originate from placental villi matrix, due to the use of oral contraceptives in women’s blood concentrations are high, whether synthesized in other maternal organs, yet