补充铁剂对上海育龄妇女贫血改善效果研究

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目的了解贫血育龄妇女补充铁剂的效果,为改善这部分人群的铁营养状况提供依据和方法。方法招募贫血的育龄妇女74名,按Hb随机分成干预组和对照组,年龄21~45岁,每日分别口服1包铁营养包(主要成分为焦磷酸铁和富马酸铁,含铁8mg)和安慰剂,连续服用3个月观察效果。干预前后两组均进行贫血相关指标检查、饮食频率调查及24h饮食回顾调查。结果干预3个月后干预组血红蛋白值由(104.9±8.84)g/L上升到(113.1±12.36)g/L,对照组由(104.4±8.96)g/L上升到(107.1±11.4)g/L,干预组显著高于对照组(P<0.05),干预组和对照组血红蛋白值达标例数分别为10例和5例,比例分别为29.4%和14.3%。总铁摄入量(饮食铁加补充的铁)与血红蛋白值的改变呈正相关(r=0.372,P<0.01)。结论连续3个月每日补充8mg铁可以改善育龄妇女的贫血状况。 Objective To understand the effects of iron supplementation in women of childbearing age at anemia and to provide basis and methods for improving iron nutrition status in this population. Methods A total of 74 women of childbearing age were enrolled in this study. According to Hb, they were randomly divided into intervention group and control group, aged 21-45 years. Oral administration of iron packs (main components were iron pyrophosphate and iron fumarate, iron 8mg ) And placebo, taking 3 consecutive months of observation. Before and after the intervention, anemia-related indexes, dietary frequency and 24-hour diet were investigated in both groups. Results The level of hemoglobin in the intervention group increased from (104.9 ± 8.84) g / L to (113.1 ± 12.36) g / L after 3 months of intervention and from (104.4 ± 8.96) g / L to (107.1 ± 11.4) g / L, the intervention group was significantly higher than the control group (P <0.05), the intervention group and the control group reached the standard number of hemoglobin were 10 cases and 5 cases, the proportions were 29.4% and 14.3%. Total iron intake (dietary iron supplemented with iron) was positively correlated with changes in hemoglobin values ​​(r = 0.372, P <0.01). Conclusions Supplementation of 8 mg iron daily for 3 consecutive months can improve anemia in women of childbearing age.
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