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目的探究血清降钙素原检测在儿科感染性疾病临床诊断中应用价值。方法 60例感染性疾病患儿以及30例非感染患儿童作为研究对象,按照儿科感染性疾病诊断标准将其分为细菌感染组(A组)、病毒感染组(B组)、非感染组(C组),每组30例。按感染程度将细菌感染组分为重症感染组(D组,17例)以及局部感染组(E组,13例);对各组小儿进行血清降钙素原、白细胞计数以及C反应蛋白水平检测。结果 A组患儿的血清降钙素原、白细胞计数、C反应蛋白水平均明显高于B组以及C组,差异均具有统计学意义(P<0.05)。D组血清降钙素原水平(7.56±2.13)ng/ml明显高于E组(1.26±0.35)ng/ml,差异具有统计学意义(P<0.05)。细菌感染患儿中,血清降钙素原阳性检出率83.3%明显高于C反应蛋白阳性检出率36.7%,差异具有统计学意义(P<0.05)。结论血清降钙素原检测能更准确检测出儿科细菌感染并有效鉴别其严重程度,在儿科感染性疾病临床诊断中具有较高的临床价值。
Objective To investigate the value of serum procalcitonin in clinical diagnosis of pediatric infectious diseases. Methods Sixty children with infectious diseases and 30 non-infected children were enrolled in this study. They were divided into bacterial infection group (A group), viral infection group (B group) and non-infected group (B group) according to the diagnostic criteria of pediatric infectious diseases C group), 30 cases in each group. Bacterial infection was divided into severe infection group (group D, 17 cases) and local infection group (group E, 13 cases) according to the degree of infection. Serum procalcitonin, white blood cell count and C-reactive protein . Results The serum procalcitonin, white blood cell count and C-reactive protein in group A were significantly higher than those in group B and C (P <0.05). The level of serum procalcitonin in group D (7.56 ± 2.13) ng / ml was significantly higher than that in group E (1.26 ± 0.35) ng / ml, the difference was statistically significant (P <0.05). In children with bacterial infection, the positive rate of procalcitonin was 83.3%, which was significantly higher than that of C-reactive protein (36.7%), the difference was statistically significant (P <0.05). Conclusion Serum procalcitonin can detect pediatric bacterial infection more accurately and identify its severity. It has high clinical value in the clinical diagnosis of pediatric infectious diseases.