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Chiral monodentate phosphoramidite ligands were conveniently prepared from 1,1′-bi-2-naphthol(BINOL) and(S)-pyrrolidine in good yields,which were effective chiral ligands in the enantioselective rhodium-catalyzed hydrogenation of dehydroamino esters and enamides at low hydrogenation pressure.High conversion rate(up to 99% for dehydroamino esters and enamides) and good enantioselectivity(up to 96.3% ee for dehydroamino esters and 91.7% ee for enamides) were obtained.
Chiral monodentate phosphoramidite ligands were conveniently prepared from 1,1’-bi-2-naphthol (BINOL) and (S) -pyrrolidine in good yields, which were effective chiral ligands in the enantioselective rhodium-catalyzed hydrogenation of dehydroamino esters and enamides at low hydrogenation pressure. High conversion rate (up to 99% for dehydroamino esters and enamides) and good enantioselectivity (up to 96.3% ee for dehydroamino esters and 91.7% ee for enamides) were obtained.