Inflammation is the primary response to infection or injury that functions to clear the injurious material or agent and promote tissue repair.However,when inflammation persists,such as chronic inflammation,it can cause tissue damage and loss of function.Persistent inflammation is closely associated with many chronic diseases,such as cancer,arthritis,osteoporosis,asthma,Alzheimer’s disease,obesity,diabetes,and cardiovascular disease [1].Numerous molecules such as cytokines,prostaglandins,and nitric oxide (NO) are involved in the induction and maintenance of the inflammatory response.Inhibition and/or down-regulation of these pro-inflammatory molecules may exert anti-inflammatory effects.