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自从Blumberg发现澳大利亚抗原(即乙型肝炎表面抗原—HBsAg)以来,不论该抗原在其检查方法、性质及其在临床、流行病学、免疫学研究方面均取得了不少新的进展,并已广泛被人们所重视。随着研究工作的不断深入,发现乙型肝炎表面抗原可分为若干亚型,这对乙型肝炎的流行病学、临床、免疫预防等方面,有着重要的意义。现将国内外近年来有关HBsAg分型研究,综述如下:
Since Blumberg discovered the Australian antigen (hepatitis B surface antigen-HBsAg), it has made a lot of new progress in the methods and properties of the antigen and its clinical, epidemiological and immunological studies Widely valued by people. With the continuous deepening of research work, we found that hepatitis B surface antigen can be divided into several subtypes, which is of great significance for the epidemiology, clinical and immunological prevention of hepatitis B. Now at home and abroad in recent years about HBsAg typing studies, summarized as follows: