克隆病(crohn disease,CD)是一种肉芽肿性炎性病变,其特征是肠壁节段性受累和透壁性炎症。可以累及消化道的任何部分,但以末端回肠和近段结肠最易受累[1]。70%的病变位于小肠,其中30%位于末端回肠[2]。早期主要表现为黏膜或黏膜下层水肿,黏膜面溃疡形成,进而病变累及肠壁全层,? Crohn disease (CD) is a granulomatous inflammatory disease characterized by segmental bowel wall involvement and transmural inflammation. Can affect any part of the digestive tract, but to the distal ileum and proximal colon most vulnerable to involvement [1]. 70% of the lesions are located in the small intestine, 30% of which are located in the terminal ileum [2]. Early mainly manifested as mucosal or submucosal edema, mucosal ulcer formation, and then lesions involving the full-thickness intestinal wall?