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目的:分析上尿路上皮肿瘤的组织学和临床特征及预后因素。方法:对60例同时性和异时性上尿路上皮肿瘤,进行回顾性总结及统计学分析。结果:单发肿瘤50例,多发10例,表浅型肿瘤18例(30.0%),浸润型42例(70.0%)。复发23例(38.3%),频率为0.76(0.15～1.71)次/年,平均间隔16.5个月。局部淋巴结转移3例,远处转移4例,其原发肿瘤均为浸润型。浸润型肿瘤或远处转移者预后较差,复发者中远期生存率较低。结论:尿路上皮肿瘤具有多发性和复发性的特点,应加强早期发现、早期诊断方面的研究。建议首次膀胱镜检查应在初诊后的第4个月,第二次间隔8个月,以后每年一次,持续10年。每两次膀胱镜检查之间,行超声波检查。
Objective: To analyze the histological and clinical features and prognostic factors of upper urothelial tumors. Methods: 60 cases of simultaneous and heterochronic upper urothelial tumors were retrospectively summarized and statistically analyzed. Results: Single tumor in 50 cases, multiple in 10 cases, 18 cases of superficial tumors (30.0%), infiltration in 42 cases (70.0%). Recurrence occurred in 23 cases (38.3%) at a frequency of 0.76 (0.15-1.71) times / year with an average interval of 16.5 months. Local lymph node metastasis in 3 cases, distant metastasis in 4 cases, the primary tumor were infiltrating type. The prognosis of infiltrating tumor or distant metastasis is poor, and the long-term survival rate of recurrence is lower. Conclusion: The urothelial tumors are characterized by multiple recurrent and recurrent. The study of early detection and early diagnosis should be strengthened. The first cystoscopy should be recommended in the first 4 months after the first interval of 8 months, after once a year for 10 years. Between every two cystoscopy, line ultrasound.