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目的探索９９ｍＴｃ培普利欧霉素（ＰＰＭ）诊断肺癌的临床价值。方法用９９ｍＴｃＰＰＭ对３０例临床诊断为肺肿瘤病人进行ＳＰＥＣＴ显像。结果肺癌与肺良性病变对９９ｍＴｃＰＰＭ的摄取和储留差异均有显著性。对肺癌，以晚期摄取比值ｘ－ｓ为判断标准，其诊断灵敏度、特异性及准确度分别为８４％、８０％和８３％，以储留指数ｘ－ｓ为阈值，则分别为８８％、１００％和９０％。肺癌不同组织学类型之间差异无显著性（Ｐ＞００５）。９９ｍＴｃＰＰＭ诊断肺癌与病理学检查结果的符合率大于ＣＴ和ＭＲＩ。结论９９ｍＴｃＰＰＭ对肺癌的鉴别诊断有一定临床价值
Objective To explore the clinical value of 99mTc-peripromycin (PPM) in the diagnosis of lung cancer. Methods SPECT imaging was performed on 30 patients with clinically diagnosed lung tumors using 99mTc-PPM. Results There were significant differences in uptake and retention of 99mTc-PPM between lung cancer and benign pulmonary lesions. For lung cancer, the late-to-advance ratio x-s was used as the criterion, with a diagnostic sensitivity, specificity, and accuracy of 84%, 80%, and 83%, respectively, and a retention index x-s as a threshold of 88%. 100% and 90%. There was no significant difference between different histological types of lung cancer (P>005). 99mTc-PPM was more accurate than CT and MRI in the diagnosis of lung cancer and pathological examination. Conclusion 99mTcPPM has certain clinical value in the differential diagnosis of lung cancer