【摘 要】
:
Drug metabolism and transport in human organs,such as in the liver,intestine,and kidney,control the concentrations of a drug and its metabolites in the circulat
【机 构】
:
Department of Biochemistry and Molecular Medicine,Cancer Center,School of Medicine,University of Cal
【出 处】
:
Acta Pharmaceutica Sinica B
论文部分内容阅读
Drug metabolism and transport in human organs,such as in the liver,intestine,and kidney,control the concentrations of a drug and its metabolites in the circulating system and target organs in a certain period of time following drug administration.The pharmacokinetic properties will consequently determine therapeutic efficacy and influence toxicological effects.Changes of drug metabolism and pharmacokinetics may result in significant inter-
Drug metabolism and transport in human organs, such as in the liver, intestine, and kidney, control the concentrations of a drug and its metabolites in the circulating system and target organs in a certain period of time the drug administration will pharmacokinetic will determine therapeutic efficacy and influence toxicological effects. Changes in drug metabolism and pharmacokinetics may result in significant inter-
其他文献
The research for antitumor therapeutics is a timeless topic and keeps pace with times,especially chemotherapy and target therapy.Drug target identification is a
不知道你有没有注意过这样一种神秘现象,当一些飞机静止在跑道上,或者缓慢地行驶在跑道上时,发动机前有时会产生一道类似龙卷风的神秘气流。一直以来,这些神秘气流形成的原因,都被藏匿于写满无数公式的论文中,所以很多人虽然对这种现象啧啧称奇,但对其背后的原因却不是很了解。有人开玩笑说,这是发动机在“尿尿”;还有人没有认真思考,就拍脑袋说这是飞机在放油。 这些神秘气流究竟是怎么形成的呢?它们对飞机是否有危害
目的 :研究口服马兜铃酸I(AA I)在大鼠体内的药物代谢动力学特点。方法 :以12 5I标记的AA I作为示踪剂 ,给予大鼠一次口服关木通水煎剂 10g·kg-1和12 5I标记AA I(含AA I37.2
20100682 Chen Zhaoxia (Beijing Jianghe Wa-ter Conservancy and Hydropower Develop-ment Co. Ltd., Beijing 100025 , China)BJS-L50 Construction Equipment of Deep Mi
Dr.Jianxin Wang is a professor of pharmaceutics at Fudan University,School of Pharmacy.He received his Ph.D.in pharmaceutics from West China University of Medic
I am very happy to present you with a Thematic Issue on "Drug Metabolism and Disposition in Diseases".Drug metabolism and disposition are essential to both drug
近百年来,人类的健康水平和医学发展有迅速的提高和重大的突破.其意义和特点有哪些?我们该怎样认识和借鉴?为此,记者采访了北京医科大学著名的医学史专家程之范教授."20世纪
Coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global crisis1,2.Infection from
Cancer is a significant global health problem and remains one of the most challenging threats to human health.Conventional cancer treatments may include surgery