,Advanced knowledge in drug metabolism and pharmacokinetics

来源 :Acta Pharmaceutica Sinica B | 被引量 : 0次 | 上传用户:shinmagi
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Drug metabolism and transport in human organs,such as in the liver,intestine,and kidney,control the concentrations of a drug and its metabolites in the circulating system and target organs in a certain period of time following drug administration.The pharmacokinetic properties will consequently determine therapeutic efficacy and influence toxicological effects.Changes of drug metabolism and pharmacokinetics may result in significant inter- Drug metabolism and transport in human organs, such as in the liver, intestine, and kidney, control the concentrations of a drug and its metabolites in the circulating system and target organs in a certain period of time the drug administration will pharmacokinetic will determine therapeutic efficacy and influence toxicological effects. Changes in drug metabolism and pharmacokinetics may result in significant inter-
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