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为探讨大鼠阴茎组织中一氧化氮合酶 (NitricOxideSynthase,NOS)分布及增龄对其的影响。本文采用NADPHd组化对不同月龄大鼠 (2、8、16、2 4月 )阴茎组织进行染色。结果显示NOS主要分布于大鼠阴茎组织平滑肌细胞 ,而内皮细胞和神经纤维含量较少 ;随年龄增加 ,阴茎组织中NOS表达逐渐减弱 ,各月龄组间差别明显。结论认为大鼠阴茎组织中NOS主要存在于平滑肌细胞 ,增龄使NOS明显减少 ,表明NOS减少可能与勃起障碍的年龄依赖性相关。
To investigate the distribution of penicillin nitric oxide synthase (NOS) and the effect of aging on rat penile tissue. In this paper, NADPHd histochemical staining of penile tissues of different age rats (2,8,16,2 April). The results showed that NOS mainly distributed in the rat penile tissue smooth muscle cells, while the content of endothelial cells and nerve fibers less; with age, the expression of NOS in penile tissue gradually weakened, and the differences between the months were significant. Conclusion NOS mainly exists in smooth muscle cells in rat penile tissues, and the number of NOS decreased significantly with aging, indicating that the decrease of NOS may be related to the age-dependent erectile dysfunction.