头部亚低温对新生儿缺氧缺血性脑损伤的临床疗效

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目的观察头部亚低温对新生儿缺氧缺血性脑损伤(HIE)的临床疗效。方法 62例患儿随机分为治疗组和对照组,对照组采用常规治疗,治疗组在其基础上行头部亚低温治疗,比较临床疗效和NBNA评分。结果治疗组总有效率87.5%,明显优于对照组的76.7%(P<0.05)。生后14d、28d,治疗组均NBNA评分明显高于对照组(P<0.05)。结论头部亚低对HIE疗效明显,副作用少,相关不良反应发生较低,能减轻颅脑损伤,值得推广。 Objective To observe the clinical effect of head hypothermia on neonatal hypoxic-ischemic brain damage (HIE). Methods Sixty-two children were randomly divided into treatment group and control group. The control group was treated with conventional therapy. The treatment group was treated with head mild hypothermia on the basis of clinical efficacy and NBNA score. Results The total effective rate was 87.5% in the treatment group, which was significantly better than 76.7% in the control group (P <0.05). On the 14th day and 28th day after birth, the NBNA score of the treatment group was significantly higher than that of the control group (P <0.05). Conclusions Head subduction has obvious effect on HIE with few side effects and low incidence of related adverse reactions, which can reduce brain injury and is worth promoting.
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