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对比分析典型哮喘患者40例与正常组健康人40例和咳嗽变异型哮喘患者50例的第一秒用力呼气量(FEV1)、用力肺活量(FVC)、第一秒用力呼气量FEV1占FVC比值(FEV1/FVC)、最高呼气流速(PEF)、残气量(RV)及残气量/肺总量(RV/TLC)指标。结果 FEV1、FVC、FEV1/FVC及PEF等肺通气功能指标:正常组最高,咳嗽变异型哮喘次之,而典型哮喘最低,(P<0.05),在激发试验前后咳嗽变异型哮喘患者肺功能存在明显可逆性改变。结论咳嗽变异型哮喘存在可逆性气流受限,确诊需要完善肺功能及支气管激发试验(BPT)或支气管舒张试验(BDT)试验。(当患者FEV1≥70%预计值时,可进一步作支气管激发试验;FEV1<70%预计值提示有气道阻塞时,宜作支气管舒张试验)~([1])
The FEV1, FVC, FEV1 and FVC of 40 patients with typical asthma and 40 patients with normal cough and 50 patients with cough variant asthma were analyzed. Ratio (FEV1 / FVC), maximum expiratory flow (PEF), residual volume (RV) and residual volume / total lung volume (RV / TLC) Results The pulmonary ventilatory function indexes of FEV1, FVC, FEV1 / FVC and PEF were the highest in normal group, followed by cough variant asthma, and the lowest in typical asthma (P <0.05). The pulmonary function of patients with cough variant asthma before and after challenge test Obvious reversible change. Conclusions There is reversible air flow restriction in cough variant asthma, and the diagnosis of pulmonary function, bronchial provocation test (BPT) or bronchodilator test (BDT) is needed. (Bronchial provocation test may be further performed when FEV1 ≥ 70% of predicted value; bronchodilator test should be performed when predicted FEV1 <70% indicates airway obstruction) ~ ([1])