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目的探讨米索前列醇在人工流产术中的应用效果。方法选取2013年2月—2014年12月于射阳县人民医院行人工流产术的患者210例,按电脑产生随机数列的方法分为观察组与对照组,各105例。观察组术前阴道内置入米索前列醇,对照组术前阴道内未置入米索前列醇。观察两组宫颈扩张情况、丙泊酚用量、手术时间、术中出血量、苏醒时间、宫颈松弛情况及并发症发生情况。结果观察组总有效率高于对照组,丙泊酚用量低于对照组,手术时间及苏醒时间短于对照组,术中出血量少于对照组,宫颈松弛差需逐号扩张率、并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论米索前列醇在人工流产术中的应用效果显著,有利于宫颈软化扩张,缩短手术时间,减少术中出血量,且并发症少。
Objective To investigate the effect of misoprostol in induced abortion. Methods Totally 210 patients undergoing artificial abortion in Sheyang County People’s Hospital from February 2013 to December 2014 were randomly divided into observation group and control group with 105 cases in each group. In the observation group, misoprostol was placed intravaginally in the vagina and no misoprostol was administered in the control group before operation. Observation of two groups of cervical dilatation, propofol dosage, operation time, intraoperative blood loss, wake time, cervical relaxation and complications. Results The total effective rate of the observation group was higher than that of the control group, the dosage of propofol was lower than that of the control group, the operation time and the recovery time were shorter than those of the control group, the bleeding volume was less than that of the control group. The incidence was lower than the control group, the difference was statistically significant (P <0.05). Conclusion The application of misoprostol in induced abortion is effective, which is beneficial to cervical softening and expansion, shortening the operation time, reducing the amount of intraoperative bleeding, and less complications.