本文研究活性炭对地高辛药物动力学的影响.受试者是6名男性和5名女性,年龄23—40岁,身体健康。除1名女性股避孕药外,其它受试者在试验期间未用任何药物。试验采取随机交叉安排,分两个试验期,两期之间至少间隔12天。第1期,受试者给予相同剂量10μg/kg 地高辛,静脉输注超过5分钟。第2期,受试者给予上述地高辛剂量的同 This study investigated the effect of activated carbon on digoxin pharmacokinetics in subjects with 6 males and 5 females, aged 23-40 years old, in good health. Except for 1 feminine birth control pill, none of the other subjects took any medication during the trial period. The experiment was conducted in a randomized crossover arrangement with two trial periods of at least 12 days between periods. In phase 1, subjects received the same dose of digoxin 10 μg / kg intravenously over 5 minutes. The second period, the subjects given the same dose of digoxin