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胆脂瘤除发生在颞骨外,额筛区、头颅、皮肤、乳房、肾和中枢神经系统也可出现。自1916年Haeggstrom首次报告一例额窦胆脂瘤后,全世界共有23例额筛区胆脂瘤的报道。作者们报告了过去九年内所见到的4例额筛区胆脂瘤:额窦2例,额骨1例,另一例由筛窦向鼻腔和蝶窦扩展。胆脂瘤发病机理有4种学说,即先天性,外伤或术后,移植及组织化生。以上四种学说中,以先天性最能被接受,即在胚胎第五周,神经沟融合时,由于上皮残余的脱落、增殖而发生。本文报告的4例中,2例支持先天学说,1例20年
Cholesteatoma occurs in addition to the temporal bone, the front sieve area, head, skin, breast, kidney and central nervous system can also occur. Since the first report of a sinusoidal cholesteatoma in 1916 by Haeggstrom, there were a total of 23 cases of screening for cholesteatoma in the world. The authors report four cases of frontotemporal cholesteatoma seen in the past nine years: 2 cases of frontal sinus, 1 case of frontal bone, and another case of ethmoid sinus spreading to nasal cavity and sphenoid sinus. Cholesteatoma pathogenesis has four kinds of theory, that is, congenital, trauma or postoperative transplantation and tissue metaplasia. Of the above four theories, congenital most acceptable, that is, in the fifth week of embryo, nerve ditch fusion, due to epithelial remnants of shedding and proliferation occurred. Of the four cases reported in this article, two supported the theory of innateness and one had 20 years