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[目的]研究轮状病毒所致轻度胃肠炎伴良性婴幼儿惊厥的临床特点及脑电图分析。[方法]选择2012年1月~2012年6月我院接诊的100例轮状病毒所致轻度胃肠炎伴良性婴幼儿惊厥患儿进行研究。比较分析患儿的一般临床资料、发病年龄、发病季节、首次惊厥发作时间、发作次数、每次发作时间、实验室检查、影像学检查、脑脊液检查和随访情况。[结果]1~2岁患儿占80%,其余年龄占20%,二者比较差异有统计学意义(χ2=72.0000,P<0.0001);冬春季节患儿占81%,夏秋季节占19%,二者比较差异有统计学意义(χ2=76.8800,P<0.0001);首次惊厥发作时间(胃肠炎后)3d以内患儿占93%,3d以上占7%,二者比较差异有统计学意义(χ2=147.9200,P<0.0001);1次病程中惊厥发作次数为1~2次患儿占92%,其余占8%,二者比较差异有统计学意义(χ2=141.1200,P<0.0001);发作时间为0~4min患儿占97%,≥4min为8%,二者比较差异有统计学意义(χ2=176.7200,P<0.0001);93%为全身强直的阵挛性发作。脑电图检查,50.00%可见小棘波,同期其他患儿小棘波发生比率为9.09%,二者比较差异有统计学意义(χ2=245.6618,P<0.0001)。随访除1例再发外,其余皆未再出现惊厥。[结论]轮状病毒所致轻度胃肠炎伴良性婴幼儿惊厥临床特点为发病年龄1~2岁多见,多为冬春季节发病,常于胃肠道症状48h内发生惊厥,发作时间常在4min以内,大多为全身强直的阵挛性发作,很多患儿脑电图出现小棘波,预后良好,再发比率低。
[Objective] To investigate the clinical features and EEG analysis of rotavirus-induced mild gastroenteritis with benign infantile convulsions. [Methods] From January 2012 to June 2012, 100 rotavirus-induced mild gastroenteritis patients with benign infantile convulsion in our hospital were selected for study. The clinical data of children, age of onset, season of onset, time of first seizure, frequency of seizures, time of each seizure, laboratory examination, imaging examination, cerebrospinal fluid examination and follow-up were compared and analyzed. [Results] 80% of children aged 1 ~ 2 and 20% of the remaining age, the difference was statistically significant (χ2 = 72.0000, P <0.0001); children in winter and spring accounted for 81%, summer and autumn accounted for 19% %, The difference between the two was statistically significant (χ2 = 76.8800, P <0.0001); the first seizure time (after gastroenteritis) within 3 days accounted for 93% of children, more than 3d accounted for 7%, the difference between the two statistics (Χ2 = 147.9200, P <0.0001). The frequency of seizures in one course was 92% in 1 ~ 2 times and the rest 8%, the difference was statistically significant (χ2 = 141.1200, P < 0.0001). The onset time was 0 to 4 minutes in children with 97% and ≥4 minutes with 8%. There was significant difference between the two groups (χ2 = 176.7200, P <0.0001); 93% of the patients had generalized clonic seizures. EEG, 50.00% visible small spikes, small spike wave occurred in other children over the same period was 9.09%, the difference was statistically significant (χ2 = 245.6618, P <0.0001). Follow-up except 1 case of recurrence, the rest are no recurrence of convulsions. [Conclusion] The clinical features of rotavirus mild gastroenteritis with benign infantile convulsion are more common in patients with onset age of 1 ~ 2 years, mostly in winter and spring seasons, and often occur within 48 hours after gastrointestinal symptoms. The onset time Often less than 4min, mostly for the onset of tonic clonic seizures, many children with small spikes EEG, good prognosis, recurrence rate is low.