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目的:探讨大剂量糖皮质激素治疗对劳力型热射病患者临床转归的影响。方法:回顾性分析2004年7月至2016年9月中山大学孙逸仙纪念医院、肇庆市第一人民医院、深圳市沙井人民医院住院的劳力型热射病患者18例的临床资料,根据患者是否使用大剂量糖皮质激素治疗分为激素组和对照组,以1∶2配对,分别使用配对Wilcoxon符号秩检验,比较大剂量糖皮质激素治疗对劳力型热射病患者住院日期和短期预后的影响。结果:激素组住院日期比对照组明显延长(P<0.05);但两组预后无显著性差异。结论:在劳力型热射病早期使用大剂量激素,可能对患者住院期间预后无明显获益。
Objective: To investigate the effect of high-dose glucocorticoid therapy on the clinical outcome of labor-induced pyrexia. Methods: A retrospective analysis of clinical data of 18 cases of labor-induced pyrethroidism hospitalized from Sun Yat-sen Memorial Hospital of Sun Yat-sen University, First People’s Hospital of Zhaoqing City and Shenzhen Shajing People’s Hospital from July 2004 to September 2016 was conducted. According to the patients’ High-dose glucocorticoid therapy was divided into hormone group and control group, paired with 1: 2, respectively, using paired Wilcoxon signed-rank test to compare the effect of high-dose glucocorticoid therapy on labor date and short-term prognosis of labor-induced pyrex disease. Results: The duration of hospitalization in hormone group was significantly longer than that in control group (P <0.05). However, there was no significant difference in prognosis between the two groups. CONCLUSIONS: The use of high-dose hormones early in labor-induced pyrexia may have had no significant benefit on the prognosis of patients during hospitalization.