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托洛尔(metoProlol,Met)是一种选择性问受体阻断剂,临床广泛应用于心血管疾病的治疗,本课题组发现Met抑制正常大鼠和自发性高血压大鼠的心肌最大缩短速率(V一),左心室内压最大上升速率(dP/dt_x),左心室内压峰值(LVSP),动脉收缩压(SBP),减慢心率(HR)的效应
MetolProlol (Met) is a selective receptor blocker, clinical widely used in the treatment of cardiovascular disease, the group found that Met inhibition of normal rats and spontaneously hypertensive rats myocardial shortening (V), the maximum rate of increase of left ventricular pressure (dP / dt_x), left ventricular peak pressure (LVSP), systolic pressure (SBP) and heart rate (HR)