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雪上一枝蒿对副交感神经有高度的兴奋作用和对心肌有直接的刺激作用。本文报告两例急性雪上一枝蒿中毒所致的眼底改变,主要表现为:(1)视网膜贫血呈灰白色,视盘境界不清;(2)视网膜动脉细小,小动脉痉挛;(3)视网膜静脉显著怒张,充盈迂曲;(4)黄斑部中心凹反光消失;(5)严重者视网膜水肿、出血。作者以家兔实验进行比较,结果与临床资料相一致。急性雪上一枝蒿中毒程度的轻重,与视网膜动脉细小的程度成正比,视网膜动脉管径的改善,即说明全身情况的好转,一旦眼底出血,可能提示脑实质出血,则预后不良。
Artemisia snow has a high degree of excitement on the parasympathetic and myocardial stimulation has a direct role. This article reports two cases of acute fundus alterations caused by Artemisia annua poisoning, mainly as follows: (1) retinal anemia was gray, unclear optic disc; (2) small retinal artery, arteriolar spasm; (3) retinal vein was significantly anger Zhang, filling tortuous; (4) macular foveal reflex disappeared; (5) severe retinal edema, bleeding. The authors compared rabbit experiments, the results consistent with the clinical data. Acute snow poisonous Artemisia degree of severity, and retinal artery is proportional to the degree of small, retinal artery diameter to improve, that is, the improvement of the general condition, once the fundus bleeding, may prompt cerebral hemorrhage, the prognosis is poor.