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广西是乙型病毒性肝炎(乙肝)高流行区,人群中乙肝表面抗原(HBsAg)携带率高达16.4％。乙肝母婴传播是乙肝传播的重要途径,文献报告 HBsAg 携带的母亲产的婴儿6个月以内约30～70％可出现HBsAg 血症,且大部份为长期携带。国内外应用 HBsAg 灭活疫苗阻断乙肝母婴传播已取得初步成功,但在广西尚未见报告。现将我们进行的一次观察结果报告如下:
Guangxi is a high endemic area of hepatitis B virus (HBV), and the population carrying rate of HBsAg is as high as 16.4%. Hepatitis B mother-to-child transmission is an important way of hepatitis B transmission. The literature reports that about 30-70% of infants born to mothers with HBsAg can develop HBsAgmia within 6 months and most of them are carried for a long time. At home and abroad the application of HBsAg inactivated vaccine to block mother-to-child transmission of hepatitis B has achieved initial success, but no report in Guangxi. We now report an observation as follows: