论文部分内容阅读
比较不同灵芝三萜单体对PC12细胞保护和自噬诱导活性的差异。结果表明,灵芝酸A、B、C、C2、DM、K对H2O2诱导的细胞损伤最大保护率分别为32.83%、12.63%、53.03%、30.30%、2.53%和25.25%;对Aβ25-35诱导的细胞损伤最大保护率分别为6.74%、29.02%、23.81%、25.07%、10.15%和5.12%;自噬诱导最大阳性率分别达到22.33%、32.67%、35.50%、28.33%、11.83%和29.50%。不同灵芝三萜单体的活性也有明显的差异,且各单体在不同活性方面均未表现出一致的强弱关系。
Comparison of different Ganoderma triterpenes monomer PC12 cell protection and autophagy induction activity differences. The results showed that the maximum protective rates of Ganoderma lucidum A, B, C, C2, DM and K against H2O2-induced cell injury were 32.83%, 12.63%, 53.03%, 30.30%, 2.53% and 25.25% The maximum protective rates of cell injury were 6.74%, 29.02%, 23.81%, 25.07%, 10.15% and 5.12%, respectively. The maximum positive rates of autophagy induction were 22.33%, 32.67%, 35.50%, 28.33%, 11.83% and 29.50 %. Different Ganoderma lucidum triterpene monomer activity also have significant differences, and each monomer in different activity did not show a consistent strength relationship.