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脑缺血耐受的实验研究发现,诱导HSPs的表达增加可能是内源性脑保护机制之一。HSP家族包括HSP90、HSP70、HSP60、HSP32、HSP27及泛素家族等。本文就这几种蛋白在沙鼠脑缺血中的研究进展作一综述。
Experimental study of cerebral ischemic tolerance found that increased expression of induced HSPs may be one of the mechanisms of endogenous brain protection. HSP family includes HSP90, HSP70, HSP60, HSP32, HSP27 and ubiquitin family. This article reviews the progress of these proteins in gerbil cerebral ischemia.