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观察硫酸依替米星对细菌性呼吸道感染的治疗作用。研究对象为确诊为细菌引起的呼吸道感染病例 15例 ,其中急性气管支气管炎 2例、慢性支气管炎急性发作 2例、肺炎 5例、肺癌伴肺部感染 6例。硫酸依替米星 2 0 0 mg,静脉滴注 ,每日 1次 ,疗程 7～ 10 d。观察指标包括咳嗽、咳痰、肺部罗音、血白细胞记数与分类、痰细菌培养、血肌酐、尿素氮等。结果显示 ,15例呼吸道感染经依替米星治疗后痊愈 5例、显效 3例、进步 5例、无效 2例 ,临床总有效率 86 .6 7% ,细菌清除率 90 .9% ,治疗前后血肌酐、尿素氮无明显升高。无其他不良反应。认为硫酸依替米星使用方便、临床疗效高、不良反应小、对肾功能无不良影响 ,可用于治疗呼吸道感染。
To observe the therapeutic effect of etimicin sulfate on bacterial respiratory tract infection. The subjects were diagnosed as respiratory tract infections caused by bacteria in 15 cases, of which 2 cases of acute tracheobronchitis, 2 cases of acute exacerbation of chronic bronchitis, pneumonia in 5 cases, lung cancer with pulmonary infection in 6 cases. Etimicin 200 mg, intravenously, once daily for 7 to 10 days. Observations include cough, sputum, pulmonary rales, white blood cell count and classification, sputum bacterial culture, serum creatinine, urea nitrogen and so on. The results showed that in 15 cases of respiratory tract infection, 5 cases were cured after treatment with etimicin, 3 cases were markedly improved, 5 cases were improved, 2 cases were ineffective, the total effective rate was 86.67% and the bacterial clearance rate was 90.9%. Before and after treatment Serum creatinine, urea nitrogen no significant increase. No other adverse reactions. Etiacal Sulfate that easy to use, high clinical efficacy, adverse reactions, no adverse effects on renal function can be used for the treatment of respiratory tract infections.