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目的探讨腹腔热灌注化疗联合体外高频热疗对晚期卵巢癌的疗效及不良反应。方法 76例晚期卵巢癌患者,全部病例均伴有腹水,合并有局部疼痛65例,予以腹腔置管灌注化疗联合体外高频热疗,观察评价其临床疗效及不良反应。结果 76例患者近期疗效较为显著,腹水控制显效9例(16.7%),有效28例(50.0%),总有效率为66.7%;疼痛控制显效15例(30.0%),有效27例(53.3%),总有效率为83.3%。结论腹腔热灌注化疗联合体外热疗治疗晚期卵巢癌是一种行之有效的姑息治疗手段。
Objective To investigate the efficacy and adverse reactions of intraperitoneal hyperthermic chemotherapy combined with high frequency hyperthermia in vitro for advanced ovarian cancer. Methods A total of 76 patients with advanced ovarian cancer were enrolled in this study. All the patients were accompanied by ascites. There were 65 cases of local pain combined with intraperitoneal perfusion chemotherapy combined with high frequency hyperthermia in vitro. The clinical efficacy and adverse reactions were observed and evaluated. Results The curative effect was obvious in 76 patients with ascites control in 9 (16.7%), effective in 28 (50.0%), total effective rate 66.7%, pain control in 15 (30.0%) and effective in 27 (53.3% ), The total effective rate was 83.3%. Conclusion Intraperitoneal hyperthermic chemotherapy combined with external hyperthermia in the treatment of advanced ovarian cancer is an effective palliative treatment.