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乙胺芴酮是一种小分子干扰素诱导剂,属芳香胺类化合物,由Adamson合成。用于抗病毒治疗。它诱导产生的干扰素对多种病毒有抑制作用,它能刺激吞噬反应。增加IgG抗体的产生。国内外已用于恶性肿瘤、血小板减少性紫癜、病毒性皮肤病等疾患的临床试验性治疗。但尚未见用于治疗矽肺的文献报导。一九七五年我所在矽肺药物筛选中发现“乙胺芴酮”对大鼠实验性矽肺预防治疗效果显著,朝阳医院已在临床试用,症状有所改善。生化指标无显著变化:X线胸片,部分病人服药前结节周围有模糊阴影,治疗后结节周围阴影消失。但有一定副作
Ethylamine fluorenone is a small molecule interferon inducer that is an aromatic amine compound synthesized by Adamson. For anti-virus treatment. Interferon, which is induced by it, suppresses many viruses and stimulates phagocytosis. Increase the production of IgG antibodies. At home and abroad have been used for clinical trials of malignant tumors, thrombocytopenic purpura, viral skin diseases and other diseases. However, no literature has been reported for the treatment of silicosis. In 1975, we found in silicosis drug screening, “ethnofluoran” experimental silicosis prevention and treatment of rats significant effect, Chaoyang Hospital has been in clinical trials, the symptoms have improved. No significant changes in biochemical indicators: X-ray, some patients before taking nodules around the fuzzy shadow, the shadow disappeared after treatment nodules. But there is a certain amount of work