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目的观察替格瑞洛联合阿司匹林治疗冠心病心绞痛的临床效果,旨在为冠心病心绞痛患者的临床治疗提供有效依据。方法选取2014年6月-2015年10月医院接诊的冠心病心绞痛的患者80例,随机分成对照组与研究组各40例。对照组给予阿司匹林进行治疗,研究组在对照组的治疗基础上加用替格瑞洛联合进行治疗。观察比较2组临床疗效与缺血性心脏病复发情况。结果研究组总有效率95.0%明显高于对照组的75.0%,差异有统计学意义(P<0.05)。研究组患者心电图改善总有效率高于对照组(P<0.05);研究组患者的不良反应发生率低于对照组(P<0.05)。结论对冠心病心绞痛患者采用替格瑞洛与阿司匹林联合治疗疗效显著,安全性较高,值得临床推广。
Objective To observe the clinical effect of ticagrelor combined with aspirin in the treatment of angina pectoris of coronary heart disease and to provide an effective basis for the clinical treatment of patients with coronary heart disease angina pectoris. Methods Eighty patients with CHD angina pectoris admitted from June 2014 to October 2015 in our hospital were randomly divided into control group and study group with 40 cases each. The control group was given aspirin for treatment. The study group was treated with ticagrelor in combination with the control group. The clinical efficacy and recurrence of ischemic heart disease in two groups were observed and compared. Results The total effective rate was 95.0% in the study group was significantly higher than 75.0% in the control group, the difference was statistically significant (P <0.05). The total effective rate of ECG improvement in study group was higher than that in control group (P <0.05). The incidence of adverse reactions in study group was lower than that in control group (P <0.05). Conclusion The combination therapy of ticagrelor and aspirin in patients with coronary heart disease and angina pectoris has significant curative effect, high safety and worthy of clinical promotion.