造影剂肾病的发病率逐年攀升,已经成为医源性急性肾衰竭的重要原因之一。造影剂肾病的防治措施主要集中于水化疗法、造影剂的选择、血液透析、N-乙酰半胱氨酸、钙离子拮抗剂、他汀类药物、抗氧化剂以及腺苷拮抗剂、血管紧张素转换酶抑制剂、L-精氨酸、心钠素、内皮素受体抑制剂、利尿剂等。但多数药物被证明无效或有害,只有少数被证明有效或可能有效。 The incidence of contrast nephropathy increased year by year, has become an important source of iatrogenic acute renal failure. Contrast agents nephropathy prevention and treatment mainly focused on the hydration therapy, contrast agent selection, hemodialysis, N-acetyl cysteine, calcium antagonists, statins, antioxidants and adenosine antagonists, angiotensin conversion Enzyme inhibitors, L-arginine, atrial natriuretic peptides, endothelin receptor inhibitors, diuretics and the like. However, most drugs prove ineffective or harmful, and only a few have been shown to be valid or likely to be effective.