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目的探讨老年人上消化道疾病患者幽门螺杆菌(HP)感染情况,为临床防治提供依据。方法对311例60岁以上老年人上消化道疾病患者进行胃镜检查,取胃黏膜组织作病理诊断和HP检测。同时与中青年患者进行对比分析。结果老年组患者HP阳性率显著高于青壮年组(P<0.01)。老年组患者慢性胃炎和胃溃疡HP阳性率分别为84.77%和83.67%,显著高于青壮年组(P<0.05);老年组患者十二指肠溃疡和胃癌HP阳性率分别为71.01%和69.05%,与青壮年组相比差异无统计学意义(P>0.05)。结论老年人上消化道疾病患者与HP感染密切相关,且感染率高,应予以积极防治。
Objective To investigate the prevalence of Helicobacter pylori (HP) infection in the elderly with upper gastrointestinal diseases and provide the basis for clinical prevention and treatment. Methods Gastroscopy was performed on 311 cases of upper gastrointestinal diseases in the elderly over 60 years of age. Gastric mucosa tissues were taken for pathological diagnosis and HP test. At the same time with young patients for comparative analysis. Results The positive rate of HP in elderly patients was significantly higher than that in young adults (P <0.01). The positive rates of chronic gastritis and gastric ulcer in the elderly group were 84.77% and 83.67%, respectively, which were significantly higher than those in the young and middle-aged adults (P <0.05). The positive rates of duodenal ulcer and gastric cancer in the elderly group were 71.01% and 69.05 %, No significant difference compared with young adults (P> 0.05). Conclusion The elderly patients with upper gastrointestinal diseases are closely related to HP infection, and the infection rate is high, should be actively controlled.