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目的探讨70 k V管电压技术对颅脑CT灌注参数及图像质量的可行性。方法 2013年10月-2014年2月拟行CT灌注检查的患者,按检查时间分为A、B两组。所有的患者采用西门子128层双源CT进行扫描。分别从每组中筛选出15例经CT检查无颅脑疾病患者的图像数据进行研究。在A、B两组患者的额叶室旁、尾状核、壳、丘脑、颞枕叶放置面积为80 mm2的感兴趣区进行测量,分别测量感兴趣区内脑血流量、脑血容量、平均通过时间。比较两组图像丘脑和额叶室旁脑白质的对比噪声比、信噪比。请2位高年资神经影像学诊断医生对两组患者的图像进行主观评分(5分=最好,1分=最差)。记录CT剂量指数、CT剂量长度乘积,计算出有效剂量来评价两组患者的辐射剂量。统计学方法采用独立样本t检验。结果两组患者感兴趣区内的灌注参数值差异无统计学意义(P>0.05)。两组患者图像质量主观评分和客观评价差异均无统计学意义(P>0.05)。B组患者的CT剂量指数、CT剂量长度乘积、有效剂量较A组患者均降低了35%。结论使用西门子第2代双源CT最新70 k V管电压技术行颅脑CT灌注检查,对颅脑灌注参数值和图像质量无明显影响,而且辐射剂量明显降低。
Objective To explore the feasibility of using 70 kV tube voltage technique for CT perfusion parameters and image quality in brain. Methods From October 2013 to February 2014, patients scheduled for CT perfusion examination were divided into A and B groups according to the examination time. All patients were scanned with Siemens 128-slice dual-source CT. Fifteen cases from each group were screened for image data from CT scan of patients without craniocerebral disease. In the A, B two groups of patients in the frontal lobe, caudate nucleus, shell, thalamus, temporal occipital lobe area of 80 mm2 area of interest were measured to measure the region of interest cerebral blood flow, cerebral blood volume, Average passage time. The contrast noise ratio and signal-to-noise ratio were compared between the two groups of image thalamus and frontal white matter. Ask 2 senior neurosurgical diagnostic physicians to subjectively rate the images of both groups of patients (5 = best, 1 = worst). Record CT dose index, CT dose length product, calculate the effective dose to evaluate the radiation dose of two groups of patients. Statistical methods using independent samples t test. Results There was no significant difference in perfusion parameters between the two groups (P> 0.05). There was no significant difference in subjective score and objective evaluation between the two groups (P> 0.05). Group B patients CT dose index, CT dose length product, the effective dose than the A group of patients were reduced by 35%. Conclusion The brain CT perfusion test using the latest 70 kV tube voltage technique of the second generation dual-source CT in Siemens has no significant effect on the parameters of brain perfusion and image quality, and the radiation dose is obviously reduced.