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本文对我室于１９９０年８月在陕北胃癌高发区土地岔乡进行胃癌普查中的３２５例自然人群胃粘膜活检标本作了幽门螺旋菌（ＨＰ）检测的研究。结果显示：该乡居民ＨＰ检出率较高（６６．７７％），并以５０～５９岁年龄组为高；ＨＰ检出部位以胃窦部为多（６５．５４％）；ＨＰ检出率随慢性胃炎病变的进展而增高（慢性浅表性胃炎为６４．３５％；慢性萎缩性胃炎为７９．３１％；慢性胃炎伴肠化生为８２．０５％，伴异型增生为８６．６７％；慢性活动性胃炎为９４．７９％）。这些特征都与本地区胃癌的发生特征相一致。从而提示，胃癌高发区居民ＨＰ感染应视为与胃癌发生相关的致病因素，亦为影响慢性胃炎发生发展的一种重要致病因素。
In this paper, we conducted a Helicobacter pylori (HP) test on gastric mucosa biopsy specimens of 325 natural populations in the Gansu Province, Gansu Province, Gansu Province in August 1990. The results showed that the detection rate of HP in the township residents was higher (66.77%) and was higher in the 50-59 age group; HP was the most detected site in the gastric antrum (65.54%); HP detection The rate increased with the progress of chronic gastritis lesions (64.35% for chronic superficial gastritis; 79.31% for chronic atrophic gastritis; 82.05% for chronic gastritis with intestinal metaplasia and 86.67 for dysplasia. %; chronic active gastritis is 94.79%). These characteristics are consistent with the occurrence of gastric cancer in this region. This suggests that HP infection in residents with high incidence of gastric cancer should be considered as a pathogenic factor related to the occurrence of gastric cancer, and it is also an important pathogenic factor that affects the occurrence and development of chronic gastritis.