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目的:观察夜香树提取物对荷瘤小鼠免疫功能的调节作用。方法:通过检测H22荷瘤小鼠碳粒廓清率、血清溶血素水平、白细胞介素-2(IL-2)和肿瘤坏死因子α(TNF-α)含量变化,观察夜香树95%乙醇提取物175,350,700 mg.kg-1 ig对荷瘤小鼠免疫功能的影响。结果:夜香树提取物可明显提高H22荷瘤小鼠廓清指数和吞噬指数,并能显著提高血清中IL-2和TNF-α的含量(P﹤0.05),但对血清溶血素水平影响不明显。结论:夜香树提取物可增强荷瘤小鼠细胞免疫功能。
Objective: To observe the regulation effect of the extract of Yuxiang tree on immune function of tumor-bearing mice. Methods: The carbon clearance rate, serum hemolysin level, interleukin-2 (IL-2) and tumor necrosis factor-α (TNF-α) Effect of 175, 350, 700 mg.kg-1 ig on immune function in tumor-bearing mice. Results: Yexiang tree extract can significantly improve the clearance index and phagocytic index of H22 tumor-bearing mice and significantly increase the levels of serum IL-2 and TNF-α (P <0.05), but have no obvious effect on serum hemolysin level . Conclusion: Yexiang tree extract can enhance cellular immune function in tumor-bearing mice.