论文部分内容阅读
目的了解福建省不同日照暴露人群维生素D(VD)营养状况及影响因素。方法 2012年10月至2013年3月通过分层整群随机抽样方法,在福建省9个地市选取1 185人,其中高日照暴露人群701人,低日照暴露人群484人,进行问卷调查、医学体检及实验室检测。结果调查人群血清25(OH)D均值为(60.46±17.12)nmol/L,VD充足、适宜和缺乏的比例分别为15.02%、59.16%和25.82%,其中秋季高日照暴露人群和冬春季低日照暴露人群25(OH)D均值分别为(66.24±17.77)nmol/L和(52.09±11.93)nmol/L,VD缺乏比例分别为13.84%和43.18%;多元线性回归分析显示月份、BMI、性别、年龄和海水鱼日平均摄入量是影响血清25(OH)D的主要因素;18岁以上糖尿病、高血压等慢性疾病患者与正常人VD水平之间不存在显著差异,在高日照暴露人群中,营养正常人群血清25(OH)D要显著高于超重和肥胖人群。结论在福建,以50 nmol/L(20ng/ml)作为评定人群VD缺乏与否的标准,大部分人群秋季VD水平是适宜的,但冬春季近半人群处于维生素缺乏状态,应引起足够重视。
Objective To understand the nutritional status of vitamin D (VD) and its influencing factors in different sunshine exposure population in Fujian Province. Methods From October 2012 to March 2013, stratified cluster random sampling method was used to select 1 185 people in 9 prefectures and cities of Fujian Province, among which 701 were exposed to high sunshine and 484 were exposed to low sunlight. Questionnaires were conducted, Medical examination and laboratory testing. Results The average serum 25 (OH) D in the survey population was (60.46 ± 17.12) nmol / L, with adequate VD and adequate and deficient proportions of 15.02%, 59.16% and 25.82%, respectively. Among the groups with high sunshine exposure in autumn and low sunshine in winter and spring The mean 25 (OH) D of exposed population was (66.24 ± 17.77) nmol / L and (52.09 ± 11.93) nmol / L respectively, and the proportion of VD deficiency was 13.84% and 43.18% respectively. Multivariate linear regression analysis showed that monthly, BMI, Age and daily average intakes of marine fish are the main factors influencing serum 25 (OH) D. There is no significant difference between VD and normal subjects in people over 18 years of age with diabetes, hypertension and other chronic diseases. In high-exposure groups , Serum 25 (OH) D in normal nutrition was significantly higher than that in overweight and obesity. Conclusions In Fujian Province, 50 nmol / L (20 ng / ml) is the standard for assessing VD deficiency in most of the population. However, the VD level in most of the population is suitable. However, nearly half of the population in winter and spring is in vitamin deficiency state, which should be given enough attention.