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该研究对8名盐敏感和13名盐抵抗正常血压受试者的盐负荷和损耗引起的24h血流动力学变化进行评估。盐负荷后,与盐抵抗组人群比较,盐敏感组受试者由于总外周血管阻力[(1791±148)比(1549±66)dyn/(cm·s),P=0.05]较高,从而平均动脉压[(96.5±2.8)比(84.2±2.7)mm Hg,1 mm Hg=0.133kPa,P<0.01]也增高;而两组人群心输出量差异无统计学意义[盐敏感(4.5±0.3)比盐抵抗(4.4±0.2)L/min]。盐损耗后,两组人群心输出量降幅差异无统计学意义,而盐抵抗组总外周血管阻力增
The study evaluated 24-h hemodynamic changes caused by salt loading and depletion in eight salt-sensitive and 13 salt-resistant normotensive subjects. After salt loading, subjects in the salt-sensitive group had higher total vascular resistance (P <0.05) than those in the salt-resistant group [(1791 ± 148) vs (1549 ± 66) dyn / (cm · s) Mean arterial pressure (96.5 ± 2.8) vs (84.2 ± 2.7) mm Hg, 1 mm Hg = 0.133 kPa, P <0.01], but there was no significant difference in cardiac output between the two groups 0.3) Salt resistance (4.4 ± 0.2) L / min]. After salt depletion, there was no significant difference in cardiac output decline between the two groups, while the total peripheral vascular resistance increased