沙利度胺是一种具有抗血管新生作用的谷氨酸衍生物,1957年10月作为孕妇镇吐镇静药物投放德国市场,1961年发现它与“海豹肢”畸形儿出生有关后撤出市场。后又被发现在抗 Thalidomide, an anti-angiogenic glutamate derivative, was introduced to the German market as a sedative drug for pregnant women in October 1957 and was found to have been withdrawn in 1961 from the birth of a “seal limb” malformation Out of the market. Later found to be resistant