自从1968年Bcrgard等首先从肾小管损害的患者尿中分离出β_2-微球蛋白以来,随着对其研究的不断深入,β_2-微球蛋白在细胞免疫学,免疫遗传学以及临床医学等方面取得了不少进展,随着免疫学的发展,人们对牙周病、龋病的发病机理有了新的认识。本文以放射免疫测定技术观测龋病、牙周病患者唾液 Since Bcrgard et al first isolated β 2 -microglobulin from the urine of patients with renal tubular lesion in 1968, with the deepening of its research, β 2 -microglobulin in cell immunology, immune genetics and clinical medicine and so on Made a lot of progress, with the development of immunology, people have a new understanding of the pathogenesis of periodontal disease and dental caries. In this paper, radioimmunoassay techniques to observe caries, saliva in patients with periodontal disease