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目的探索依达拉奉联合阿司匹林治疗急性脑梗死的效果以及不良反应发生状况。方法在2013年6月-2016年12月来茂名市人民医院就诊的急性脑梗死患者中选出85例为研究对象,随机分为对照组和观察组,对照组给予对症疗法联合阿司匹林治疗,观察组在对照组的基础上加用依达拉奉治疗,就两组患者的临床治疗效果进行比较。结果观察组总有效率为93.02%,高于对照组的76.19%,差异有统计学意义(P<0.05);观察组无死亡,对照组死亡率为11.90%,差异有统计学意义(P<0.05);观察组存活患者的NIHSS评分低于对照组,差异有统计学意义(P<0.05);在不良反应发生率上两组差异无统计学意义(P>0.05)。结论依达拉奉与阿司匹林联合治疗急性脑梗死有助于促进患者神经功能的恢复,挽救生命,且安全性较高,值得推广。
Objective To explore the effect of edaravone combined with aspirin in the treatment of acute cerebral infarction and the incidence of adverse reactions. Methods A total of 85 acute cerebral infarction patients from Maoming People’s Hospital from June 2013 to December 2016 were enrolled in the study. They were randomly divided into control group and observation group. The control group was treated with symptomatic therapy combined with aspirin. Group based on the control group plus edaravone treatment, the clinical efficacy of two groups of patients were compared. Results The total effective rate in observation group was 93.02%, which was higher than 76.19% in control group (P <0.05). There was no death in observation group and 11.90% in control group (P < 0.05). The NIHSS score of survivors in the observation group was lower than that of the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion The combination of edaravone and aspirin in the treatment of acute cerebral infarction can help to promote the recovery of neurological function, save lives and have higher safety. It is worth to be popularized.