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绞股蓝总皂甙(GPS100mg/kg)明显抑制急性栓塞性脑缺血所致的脑血管通透性增加,使伊文思兰透过减少,脑组织脂质过氧化物丙二醛含量降低.同时,GPS100μg/ml能对抗电解克氏液所致的离体兔基底动脉灌流压升高。说明GPS能保护脑血管免受自由基损伤。
Gynostemma total saponin (GPS100mg/kg) significantly inhibited the increase of cerebral vascular permeability caused by acute cerebral ischemia, reduced Evans blue, and reduced the content of lipid peroxide MDA in brain tissue. Meanwhile, GPS100μg The perfusion pressure of isolated rabbit basilar arteries caused by electrolysis of Krebs liquid can be increased by /ml. Explain that GPS can protect cerebral blood vessels from free radical damage.