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小细胞肺癌对化疗及放疗的疗效显著,已不需要手术治疗。因此,准确地鉴别小细胞癌与其他类型的肺癌十分重要。作者复查了1970～1978年 Johns Hopkins 医院40例活检证实为小细胞肺癌并进行过化疗和放疗的死者尸检记录。复查结果发现40例中有5例为非小细胞癌,6例为混合型癌,29例为小细胞癌。5例非小细胞肺癌中3例为鳞状细胞癌,1例为腺癌,1例为未分化大细胞癌。其临床表现均为局限性病变(即肿瘤不超出同侧胸腔及同侧锁骨上淋巴结),病程进展也比较慢,与一般的小细胞肺癌不同。6例混合型癌中
Small cell lung cancer has a significant effect on chemotherapy and radiotherapy, and no surgery is required. Therefore, it is very important to accurately identify small cell carcinoma and other types of lung cancer. The authors reviewed autopsy records of 40 deceased patients who had been biopsy-proven for small cell lung cancer, chemotherapy, and radiotherapy from 1970 to 1978 in the Johns Hopkins Hospital. The results of the review revealed that 5 out of 40 patients had non-small cell carcinoma, 6 had mixed cancer, and 29 had small cell carcinoma. Of 5 cases of NSCLC, 3 were squamous cell carcinoma, 1 was adenocarcinoma, and 1 was undifferentiated large cell carcinoma. Its clinical manifestations are localized lesions (ie, the tumor does not exceed the ipsilateral thorax and ipsilateral supraclavicular lymph nodes), and the progression of the disease is relatively slow, unlike the general small cell lung cancer. 6 cases of mixed cancer