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目的探讨内镜下黏膜染色联合黏膜切除对大肠侧向发育型肿瘤(LST)的临床诊治价值。方法对4018例肠镜检查中发现的可疑病灶采用0.4%靛胭脂行黏膜染色,观察病变大小和腺管开口类型,进行EMR或EPMR治疗。结果LST检出率为0.75%。形态分型以颗粒均一型、结节混合型为主,腺管开口类型以IIIL和IV型为多。EMR治疗21例,EPMR治疗9例,术中出血4例,以钛夹和APC止血。无肠穿孔发生。结论内镜下黏膜染色联合黏膜切除术是诊治LST有效和安全的方法。
Objective To investigate the value of endoscopic mucosal staining combined with mucosal resection in the diagnosis and treatment of laterally developed large intestine tumors (LST). Methods The suspected lesions found in 4018 cases of colonoscopy were stained with 0.4% gingival mucosa, and the size of the lesion and the type of glandular opening were observed. EMR or EPMR was performed. Results The LST detection rate was 0.75%. The morphological typing was mainly composed of uniform particles and mixed nodules. The type of glandular ostia was mostly IIIL and IV. There were 21 cases treated with EMR, 9 cases treated with EPMR, 4 cases intraoperative bleeding, and hemostasis with titanium clip and APC. No intestinal perforation occurred. Conclusion Endoscopic mucosal staining combined with mucosal resection is an effective and safe method for diagnosis and treatment of LST.