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本文应用免疫组织化学PAP法对40例侵蚀性葡萄胎雌激素受体(ER)及绒毛膜促性腺激素β-亚单位(β-HCG)进行研究。结果发现ER与和β-HCG表达有高度一致性(P<0.001)。ER~+组病死率低于ER~-组(P=0.018)。生存组与病死组的β-HCG量差异无显著性,P>0.05。故认为侵蚀性葡萄胎ER表达在一定程度上能影响患者的预后,对患者的治疗和预后的判断可能更优于β-HCG的检测。
In this study, we used immunohistochemical PAP method to study the estrogen receptor (ER) and chorionic gonadotropin beta-subunit (beta-HCG) in 40 patients with invasive mole. The results showed that ER and β-HCG expression was highly consistent (P <0.001). The mortality of ER ~ + group was lower than that of ER ~ - group (P = 0.018). There was no significant difference in the amount of β-HCG between the survival group and the dead group (P> 0.05). So that the expression of ER in invasive hydatidiform mole can affect the prognosis of patients to some extent, the treatment of patients and prognosis may be better than β-HCG detection.