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帕金森病 (Ｐａｒｋｉｎｓｏｎ ｓｄｉｓｅａｓｅ,ＰＤ)的病因和发病机制至今尚不清楚。近年来人们开始注意到遗传和环境对ＰＤ发生的相对作用。有关ＰＤ家族聚集性和多病例家族常染色体显性遗传方式的研究也提示遗传因素在ＰＤ的病因学中起基础性作用[1 ,2 ] 。ＰＤ以黑质多巴
The etiology and pathogenesis of Parkinson’s disease (PD) are still unclear. In recent years, people began to notice the relative role of genetics and environment in PD. Studies of PD family clustering and multi-case family autosomal dominant inheritance also suggest that genetic factors play a fundamental role in the etiology of PD [1, 2]. PD to black dopa