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目的探讨老年人群中心血管危险因素与动脉硬化之间的关系。方法自2014年7月至2015年8月,在北上海10个社区纳入1 599名老年居民(年龄≥65岁)。采用Sphygmo Cor动脉硬化检测仪检测患者颈-股脉搏波传导速度(cf-PWV)。心血管危险因素采用问卷、体格检查或标准检测方法获得。采用SPSS 20.0统计软件包进行统计分析。结果 cf-PWV与高龄、肥胖、高血压、糖尿病、脂质代谢异常等心血管危险因素均呈显著相关性(P<0.001)。而且,随着心血管危险因素个数的累积,cf-PWV呈逐渐上升的趋势。这种趋势在全部人群、男性及女性中均达到了统计学显著性标准(P<0.001)。结论动脉硬化的进展与高龄、肥胖、高血压、糖尿病、脂质代谢异常等心血管危险因素的累积紧密相关。
Objective To investigate the relationship between cardiovascular risk factors and arteriosclerosis in the elderly population. Methods From July 2014 to August 2015, 1,599 elderly residents (aged ≥65 years) were enrolled in 10 communities in North Shanghai. The Sphygmo Cor arteriosclerosis detector was used to measure the cervical-femoral pulse wave velocity (cf-PWV). Cardiovascular risk factors using questionnaires, physical examination or standard testing methods. SPSS 20.0 statistical software package for statistical analysis. Results There was a significant correlation between cf-PWV and cardiovascular risk factors such as age, obesity, hypertension, diabetes and lipid metabolism (P <0.001). Moreover, as the number of cardiovascular risk factors accumulated, cf-PWV showed a gradual upward trend. This trend reached a statistically significant level in all populations, both men and women (P <0.001). Conclusion The progress of atherosclerosis is closely related to the accumulation of cardiovascular risk factors such as aging, obesity, hypertension, diabetes and lipid metabolism.