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目的:比较新疆维吾尔族(维族)与汉族冠心病患者冠状动脉粥样硬化斑块的64排螺旋CT特征与冠心病危险因素,探讨2个民族冠心病发病可能原因。方法:同期64排螺旋CT冠状动脉造影确诊为冠心病的维族患者152例及汉族患者304例,分析其斑块成分、部位、血管狭窄程度及梗阻性斑块(狭窄≥50%的斑块)累及冠状动脉的分支数,并采集患者性别、年龄、身高、体质量及高血压病史、糖尿病病史、吸烟史、家族史,三酰甘油、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇水平进行比较。结果:维族冠心病患者斑块发生率高于汉族(P<0.05),斑块发生在回旋支的比例高于汉族(P<0.05),斑块引起管腔中、重度狭窄比例高于汉族(P<0.05),梗阻性斑块累及多支比例高于汉族(P<0.05);2个民族斑块成分差异无统计学意义(P>0.05)。维族冠心病患者体质量指数高于汉族(P<0.05),2个民族高血压、糖尿病、吸烟史、三酰甘油、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇比较差异无统计学意义(P>0.05)。结论:2个民族冠状动脉粥样硬化斑块特征存在差异,维族冠状动脉粥样硬化斑块发生率高、病变程度较汉族重,可能与维族体质量指数高于汉族有关。
Objective: To compare the characteristics of 64-slice spiral CT and risk factors of coronary heart disease in patients with coronary atherosclerotic plaques in Xinjiang Uygur (Uygur) and Han patients with coronary heart disease and explore the possible causes of coronary heart disease in the two ethnic groups. Methods: Fifty-eight Uygur patients with coronary heart disease and 304 patients with Han were diagnosed by 64-slice spiral CT coronary angiography. The plaque composition, location, degree of vascular stenosis and obstructive plaque (plaque ≥50%) were analyzed. Involved the number of coronary artery branches, and collected the patient’s gender, age, height, body weight and history of hypertension, diabetes history, smoking history, family history, triglyceride, total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol Level comparison. Results: The incidence of plaque in Uighur coronary heart disease patients was higher than that in Han people (P <0.05). The plaque incidence in the circumflex branch was higher than that in Han people (P <0.05) P <0.05). The proportion of obstructive plaques involved in multiple branches was higher than that in Han (P <0.05). There was no significant difference in plaque composition between the two ethnic groups (P> 0.05). The body mass index of Uighur coronary heart disease patients was higher than Han nationality (P <0.05). There was no significant difference in hypertension, diabetes mellitus, smoking history, triglyceride, total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol Significance (P> 0.05). CONCLUSION: There are differences in coronary atherosclerotic plaque characteristics among the two ethnic groups. The incidence of coronary artery atherosclerotic plaques in Uighurs is higher than that in Han people, which may be related to the higher body mass index of Uighur than Han nationality.