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早在1957年,人们就知道哺乳动物脑内含有多巴胺(DA),其含量约占全脑儿茶酚胺(CA)总量的50％,但当时仅把 DA 看作是合成去甲肾上腺素(NE)的原料,其后,通过广泛研究 DA 的生化、药理及其在精神分裂症和震颤麻痹(帕金森病)中的作用,证实 DA 不仅是合成 NE 的原料,
As early as 1957, it was known that mammalian brains contained dopamine (DA) in an amount of about 50% of the total catecholamine (CA) in the whole brain, but at that time only DA was considered as a synthetic norepinephrine (NE) After that, by extensively studying the biochemical and pharmacological effects of DA and its role in schizophrenia and Parkinsonism (Parkinson’s disease), it was confirmed that DA is not only a raw material for the synthesis of NE,