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慢性髓细胞白血病(CML)为一组克隆性疾病。BCR~+的患者具有典型实验室与临床特征,即慢性粒细胞白血病(CGL);少数BCR~-者,存在骨髓病态造血,外周血单核细胞增多大于1.0×10~9/L,被划分为慢性粒-单核细胞白血病(CMML);尚有少部分BCR~-者,不论其单核细胞绝对或相对升高,患者具有不同于CMML的骨髓病态造血特征,生存期明显短于CMML患者,部分学者认为是非典型慢性髓细胞白血病(aCML)。最近FAB协作组对51例CML分析后提出,CGL、
Chronic myeloid leukemia (CML) is a group of clonal diseases. Patients with BCR~+ have typical laboratory and clinical features, namely chronic myelocytic leukemia (CGL); a minority of BCR~-, with hematopoietic bone marrow, peripheral blood mononuclear cells greater than 1.0 x 10~9/L, were divided into For chronic myelomonocytic leukemia (CMML); there are still a small number of BCR~-, no matter whether their mononuclear cells are absolutely or relatively elevated, the patient has different hematopoietic characteristics from CMML, and the survival period is significantly shorter than that of CMML patients. Some scholars believe that atypical chronic myeloid leukemia (aCML). Recently, the FAB Collaborative Group proposed a CGL analysis of 51 cases of CML.