论文部分内容阅读
目的 探讨肝癌根治性切除后联合肝动脉栓塞化疗和门静脉化疗对预防复发和提高生存率的作用。方法 回顾分析 1993年 1月～ 1997年 12月治疗符合根治性切除的原发性肝癌患者 10 2例。其中术后联合HACE和PVC(观察组 ) 49例 ,未作特殊处理 5 3例 (对照组 ) ,全部患者随访 3年以上。将两组作对比分析。结果 患者 1、3、5年复发率观察组分别为 10 .2 %、36 .7%、6 1.2 % ;对照组分别为 37.7%、73.6 %、79.2 %。患者 1、3、5年生存率观察组分别为 95 .9%、5 7.1%、48.9% ;对照组分别 77.3%、37.7%、2 8.0 %。结论 肝癌根治性切除术后 ,通过联合应用HACE和PVC可以明显降低术后复发率 ,提高术后生存率 ,是提高肝癌术后疗效的有效方法。
Objective To investigate the effect of combined hepatic arterial chemoembolization and portal vein chemotherapy in preventing recurrence and improving survival after radical resection of liver cancer. Methods A total of 102 patients with primary liver cancer who underwent radical resection from January 1993 to December 1997 were retrospectively analyzed. Among them, 49 cases were treated with HACE and PVC (observation group) and 53 cases were not treated with special treatment (control group), all patients were followed up for more than 3 years. The two groups for comparative analysis. Results The recurrence rates of patients in one, three, and five years were 10.2%, 36.7% and 62.2% respectively, while those in control group were 37.7%, 73.6% and 79.2% respectively. The 1, 3, 5-year survival rates in the observation group were 95.9%, 51.1% and 48.9% respectively, while those in the control group were 77.3%, 37.7% and 28.0% respectively. Conclusions After radical resection of hepatocellular carcinoma, the combination of HACE and PVC can significantly reduce the recurrence rate and improve the postoperative survival rate, which is an effective method to improve the postoperative efficacy of liver cancer.