蔬菜瓜果是人类与动物的主要食物.经过周密的基因改造过程,已在一些可食用的植物中引进不同的目的基因,尤其是某些病原体的相关基因,导致这些转基因植物在其可食用器官(例如果实、叶、茎、根等)内大量生产免疫原,这些永久性的转基因植物更会一代又一代地持续生产其独特的抗原.这些植物不仅可成为低成本及容易生产大量抗原的工厂,并且无需纯化抗原便可供人或动物直接用作口服疫苗(例如番茄、马铃薯、蔬菜等).本文介绍了转基因蔬果用作口服疫苗的研究现况. Vegetables and fruits are the main food for human beings and animals.After careful genetic modification process, different etiologic genes have been introduced into some edible plants, especially the related genes of certain pathogens, which lead to the transformation of these transgenic plants in their edible organs (Such as fruits, leaves, stems, roots, etc.), these permanent transgenic plants will continue to produce their unique antigens from generation to generation. These plants not only make it a low-cost and easy-to-produce factory for large quantities of antigens , And can be directly used by humans or animals as oral vaccines (such as tomatoes, potatoes, vegetables, etc.) without the need to purify the antigen.This article describes the research status of transgenic fruits and vegetables used as oral vaccines.