目的:提高晚期前列腺癌的治疗效果。方法:回顾性分析采用睾丸切除术、内分泌治疗、放射治疗和同位素治疗等综合治疗的41例晚期前列腺癌患者资料。结果:41例经随访3～12个月,尿路梗阻症状均有不同程度改善,前列腺明显缩小,血清前列腺特异性抗原迅速降低,骨痛缓解。结论:积极的综合治疗能明显提高患者的生活质量 Objective: To improve the treatment of advanced prostate cancer. METHODS: Retrospective analysis of 41 patients with advanced prostate cancer who underwent comprehensive treatment with orchiectomy, endocrine therapy, radiotherapy, and isotope therapy was performed. Results: 41 cases were followed up for 3 to 12 months, urinary tract obstruction symptoms have improved to varying degrees, the prostate was significantly reduced, serum prostate-specific antigen decreased rapidly, and bone pain eased. Conclusion: Active comprehensive treatment can significantly improve patients’ quality of life