论文部分内容阅读
氟卡胺已广泛用于治疗成年人室上性和室性心动过速,本品副作用少,特别对心肌功能良好的室上性心律失常(SVT)疗效显著。小儿自发性SVT中常规药无效者占10%,为寻找有效、低毒且给药方便的抗心律失常药,作者评价了氟卡胺对16例小儿和青年SVT的疗效和副作用。材料与方法:SVT患者16例,年龄1个月～32岁(平均13岁)。标准心内电生理检查证实房室结折返4例,旁路折返7例,房性自律性心动过速2例,心房扑动3例.其中12例心脏解剖学正常,4例有先天性心脏病.给氟卡胺前后分别行ECG、M型及二维超声心动图、胸X线及24小时动态心电图监测.氟卡胺2.8mg/kg/d,分 2次服,如3天后不能控制则剂量增至5.6mg/kg/d;服药3天后
Flecainide has been widely used in the treatment of supraventricular and ventricular tachycardia in adults, less side effects of this product, especially for myocardial function of supraventricular arrhythmias (SVT) significant effect. Spontaneous SVT in children with conventional drugs ineffective accounted for 10%, in order to find effective, low toxicity and convenient administration of anti-arrhythmic drugs, the authors evaluated the efficacy and side effects of flecainide in 16 cases of pediatric and young SVT. Materials and Methods: 16 patients with SVT, aged 1 month to 32 years (mean 13 years). Standard electrophysiological examination confirmed atrioventricular nodal return in 4 cases, bypass reentry in 7 cases, atrial tachycardia in 2 cases, atrial flutter in 3 cases, 12 cases of normal cardiac anatomy, 4 cases of congenital heart Before and after flecainide were ECG, M-mode and two-dimensional echocardiography, chest X-ray and 24-hour Holter monitoring. Flecainide 2.8mg / kg / d, 2 times service, such as 3 days after the uncontrollable Then the dose increased to 5.6mg / kg / d; 3 days after taking the drug